What does the Bible say about a single leading a ministry? As far as I've seen, there hasn't been any single officially hired to lead a ministry full-time. And often, when I hear about ministries looking for full-time ministers, they ask for couples -- a basic criterion. I feel like a lot of amazing disciples are overlooked for such ministry opportunities because they are simply not married. What are your thoughts on this?

Ironically, the Bible seems to have ONLY singles leading ministries! (E.g., Jesus, Paul, Peter...) The married apostles had the chance to take their wives with them, but Paul wasn’t married. Timothy too appears to be single. In addition, the only women clearly receiving financing from the church were single women age 60+ (1 Tim 5). Of course there's an apparent exception with Priscilla and Aquila (Acts 18), though who knows whether they were paid ("on staff").

You may have a point about people being overlooked simply because they are not (yet) married. Yet I do know a number of singles on staff, as well as marrieds who serve while their spouses are in other professions. The important thing is to remain open. If the Bible doesn't forbid it, it might just work. Especially when it's exemplified in Scripture itself!